Glucosamine and Chondroitin have been used to treat
osteoarthritis throughout the world for over thirty years. Recently, veterinarians in the United
States have started to turn to these compounds for their patients and have been
extremely happy with the results. These products are proving to be one of the
safest and best treatments for the crippling effects of osteoarthritis that
affects millions of aging dogs.
There are many different joints that can be affected by
osteoarthritis in the dog, but by far, the most common is the hip joints. Hip
Dysplasia is very common in many of the larger breeds of dogs. This condition
greatly exacerbates the normal wear on the smooth cartilage protecting the bony
surface of the joint. When this cartilage wears away there is a bone to bone
contact, which creates the pain seen with arthritis. Even dogs that do not have
hip dysplasia may have a decrease in this cartilage as they age, and will show
signs of arthritis. In addition, aging dogs may also have arthritis in their
knees, elbows, and shoulders and cartilage loss or damage that respond to
glucosamine and chondroitin.
glucosamine and chondroitin found?
Glucosamine and chondroitin are normal substances found
in the body of living animals. They are at their highest concentration in
cartilage. Unfortunately, through degradation during digestion and processing,
almost all of the glucosamine in an animal's diet is unavailable for use. The
body, therefore, synthesizes most of its own glucosamine through a biochemical
reaction utilizing glucose. In normal healthy animals the body is able to
synthesize enough glucosamine to keep the existing cartilage healthy, but when
the animal ages or there is damage to joint cartilage it cannot produce enough
to keep up with the body's needs. This is where a supplemental form of
glucosamine is needed.
How do glucosamine
and chondroitin work?
Glucosamine provides the building blocks to synthesize
new cartilage. In a nutshell, cartilage consists of several different cells,
one of which is chondrocytes. Chondrocytes are responsible for synthesizing new
cartilage. Through normal wear, cartilage is constantly being broken down and
replaced. When a dog has hip dysplasia or ages, the chondrocytes do not have
the building blocks available to them to build enough new cartilage to keep up with
the breakdown of the old cartilage. Glucosamine provides the building blocks to
synthesize new cartilage, called glycosaminoglycans. The glycosaminoglycans are
combined with hyaluronic acid to make the substance proteoglycans. The
proteoglycans and collagen are the main structures of cartilage.
Chondroitin blocks destructive enzymes that break down
cartilage in the joint. Chondroitin also is one of the products necessary for
the synthesis of glycosaminoglycans. But it probably plays a more important
role by combating and neutralizing destructive enzymes in the joint. There is
always a low level of destructive enzymes found in the joint, but when injury
or abnormal wear occurs, the destructive enzymes and agents increase
accelerating cartilage destruction. When chondroitin is added to the diet it
helps to reduce the level of these destructive enzymes.
While almost every canine joint supplement uses a
synthetic form of glucosamine and chondroitin, HardyPet has chosen the natural
forms which have higher bioavailability, provide better glycosaminoglycan
conversion, and do not contain the harmful substances normally associated with
Glucosamine: A 2-amino derivative of glucose
which is obtained through the hydrolysis of chitin, a polysaccharide found in
the shell of crustaceans. HardyPet formulas contain natural glucosamine found
in Refined Oyster Shell.
Chondroitin: A naturally occurring product found in animal cartilage. HardyPet formulas contain natural chondroitin found in premium Shark Cartilage.
The use of natural ingredient forms whenever possible,
and the precise combination of other synergistic compounds, make HardyPet Complete
the best holistic option for dogs with Osteoarthritis, breeds that are prone to
hip dysplasia, and all breeds suffering from age related mobility issues.